BCH 5045     GRADUATE SURVEY OF BIOCHEMISTRY     OnLine, FALL 2011

Animated GIFs above are PDB entries 1ffk, 1fka and 1fjg from The RCSB PDB WWW address: http://www.rcsb.org/pdb/. The original journal reference for the BNL PDB is: F.C.Bernstein, T.F.Koetzle, G.J.Williams, E.E.Meyer Jr, M.D.Brice, J.R.Rodgers, O.Kennard, Shimanouchi, M.Tasumi. The Protein Data Bank: a computer-based archival file for macromolecular structures. J. Mol. Biol. 112 pp. 535 (1977). Can you guess what the rotating structures are? See bottom of page for the answer.

24 of 34 students submitted evaluations for a 71% submission rate. Thank you.

 

Dr. Charles Guy
Dept. of Env. Hort.
Box 110670
Gainesville, FL 32606
Phone: 352-273-4528
Fax: 352-392-3870
Email: clguy@ufl.edu

GEE WIZ FACTOID: Estimates by some have suggested that the human body may use and recycle the equivalent of ~160 kg of ATP daily!

If the DNA in our chromosomes were stretched out in a line end to end would it be more than 6 inches, 6 feet, 60 feet or 600 feet long? Answer can be found at: http://nature.ca/genome/03/a/03a_11a_e.cfm

 

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Answer for above.

Ribosomes are composed of two subunits: a large subunit, shown on the left, and a small subunit, shown on the right. The term "small" is relative as both the large and the small subunits are huge compared to say the average protein. Both subunits are composed of long strands of RNA, shown here in orange and yellow. Protein chains are shown in blue. When making a new protein, the two subunits lock together with the messenger RNA threaded through them. The ribosome then advances down the messenger RNA three nucleotides at a time, building a new protein one amino acid after another.

updated 7/11/11